ORTHOFLEX® forte//Protect cartilage and greatly improve the joints mobility

Prefilled syringes|
Synovial fluid supplement
ORTHOFLEX forte® is a prefilled syringes having aluminum blister for sealing that assure 3 years guarantee of validity, sterilized by autoclaving.
Sodium Hyaluronate 30 mg/2ml
Description
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Orthoflex one is single treatment , viscoelastic gel injectable prefilled syringe used intra articular for treating arthritis. It is similar to synovial fluid, a substance that occurs naturally in the joints, synovial fluid acts as a lubricant and shock absorber.
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Orthoflex one is cross-linked hyaluronate 60mg/3ml solution of highly purified sodium hyaluronate , + chondroitin sulfate 90mg/3ml ,with high molecular weight that guarantees its excellent efficiency and a strong therapeutic effect( 3,0 million daltons).
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Obtained by bio fermentative process, synthetic origin gives a complete safety eliminating any allergic reactions.
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Orthoflex one is a prefilled syringes having aluminum blister for sealing that assure 3 years guarantee of validity , sterilized by autoclave,
Effects
Chondroitin Sulfate and Hyaluronic Acid with Orthoflex one in the treatment of degenerative joint disease.
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Hyaluronan contributes to the synovial fluid’s lubricating properties and also controls fluid flow into and out of the joint space.
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Injected into knee joints with osteoarthritis (OA) to ease pain and stiffness. Chondroitin sulfate, is a structural component of aggrecan in cartilage and provides much of its resistance to compression.
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Chondroitin sulfate (CS) and hyaluronic acid (HA) induces cartilage destruction and acts as a mediator of the inflammatory response.
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Using Chondroitine Sulfate as a cross-linking agent increase biocompatibility and biodegradability native polymer and creates premises delay of cartilage degeneration and even supports regeneration cartilage structure.
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Orthoflex one –improved by cross linking , preponderantly elastic, confers capacity mechanic protection increased and improved lubrication( ≥45Pa characteristic human synovial fluid)
Indications
The treatment consists in administration of intra-articular single treatment :
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Orthoflex one is indicated for the symptomatic treatment of mild of severe osteoarthritis.
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Orthoflex one is recommended for patients that have joints pain coupled with reduced mobility. These symptoms can occur as a result of degenerative disease or trauma.
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Orthoflex one treats pain and restricted mobility and elasticity , protect cartilage as a result of traumatic pathology in the knee joint and other synovial joints( hip, ankle, shoulder, elbow, wrist, fingers, toes, and the temporomandibular and facet joints)
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Is also indicated for the reduction of post –arthroscopy pain.
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Is contraindicated in children, pregnant or breast –feeding women.
Physicochemical Properties:
The treatment consists in administration of intra-articular single treatment :
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Treatment 1injection
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60mg/3ml (2%) sodium hyaluronate
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90mg/3ml chondroitin sulfate
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Average molecular weight 3 million Daltons (viscometric data)
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Elasticity minimum 110 Pa (2.5Hz, maximum effort)
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Viscosity minimum 45 Pa (2.5Hz, maximum effort)