Description

• Orthoflex one is single treatment , viscoelastic gel injectable prefilled syringe used intra articular for treating arthritis. It is similar to synovial fluid, a substance that occurs naturally in the joints, synovial fluid acts as a lubricant and shock absorber.

• Orthoflex one   is cross-linked hyaluronate 60mg/3ml solution of highly purified sodium hyaluronate , + chondroitin sulfate 90mg/3ml ,with high molecular weight that guarantees its excellent efficiency and a strong therapeutic effect( 3,0 million daltons).

• Obtained by bio fermentative process, synthetic origin gives a complete safety eliminating any allergic reactions.

• Orthoflex one is a prefilled syringes having aluminum blister for sealing that assure 3 years guarantee of validity , sterilized by autoclave,

Effects

Chondroitin Sulfate and Hyaluronic Acid with Orthoflex one in the treatment of degenerative joint disease.

• Hyaluronan contributes to the synovial fluid’s lubricating properties and also controls fluid flow into and out of the joint space.

• Injected into knee joints with osteoarthritis (OA) to ease pain and stiffness. Chondroitin sulfate, is a structural component of aggrecan in cartilage and provides much of its resistance to compression.

• Chondroitin sulfate (CS) and hyaluronic acid (HA) induces cartilage destruction and acts as a mediator of the inflammatory response.

• Using Chondroitine Sulfate as a cross-linking agent increase biocompatibility and biodegradability native polymer and creates premises delay of cartilage degeneration and even supports   regeneration cartilage structure.

• Orthoflex one –improved by cross linking , preponderantly elastic, confers capacity mechanic protection increased and improved lubrication( ≥45Pa characteristic human synovial fluid)